Simian Virus 40 Infection Triggers a Balanced Network That Includes Apoptotic, Survival, and Stress Pathways

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Simian virus 40 infection triggers a balanced network that includes apoptotic, survival, and stress pathways.

The infection process by simian virus 40 (SV40) and entry of its genome into nondividing cells are only partly understood. Infection begins by binding to GM1 receptors at the cell surface, cellular entry via caveolar invaginations, and trafficking to the endoplasmic reticulum, where the virus disassembles. To gain a deeper insight into the contribution of host functions to this process, we stud...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2010

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.01735-09